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Upon the completion of the acquisition of Sun by Oracle Corporation, Oracle executives began to outline a platform system vision of the future Key in that vision is the emergence of integrated software and hardware solutions The Oracle Exadata Database Machine represents the first such platform In this initial chapter, we ve outlined at an introductory level what this platform is Oracle has been pretty clear that the vision for the future extends into the realm of end-to-end hardware and software solutions, going beyond simply databases and eventually including applications The transaction processing and data warehousing data models of those applications reside in Oracle databases and hence, can reside on the Oracle Exadata Database Machine today There is great potential for Oracle to further package and bundle such solutions, easing deployment and use, speeding up performance, and assuring even better security and availability Of course, most applications also rely on middle-tier components While the discussion of deployment of such components is outside the scope of this book, Oracle s extensive array of Sun servers can certainly also meet those needs With the continued introduction of other tightly integrated Oracle software and Sun hardware configurations such as Exalogic, a platform designed to speed WebLogic and Java-based applications, end-toend solutions from Oracle promise to move deployment strategies from custom design, build, and integration to rapid assembly of well-defined components Oracle is clearly evolving the administration and maintenance of its software toward being more self-tuning and self-managing Enterprise Manager Grid Control continues to complement this direction by providing a monitoring and management interface not only for the database but also for middleware and applications Where organizations do not want to do the maintenance themselves, there are initiatives underway within Oracle and among its partners to provide managed services for these platforms Oracle also positions these platforms to fill critical roles in private cloud or public cloud deployment scenarios, where organizations can obtain the benefits of Software-as-a-Service (SaaS) when deploying their own hardware and software platform infrastructure or when accessing the infrastructure of an Oracle platform services provider The Oracle Exalogic Elastic Cloud includes Exalogic and Exadata as key middleware and database platforms linked via InfiniBand that are deployed for such cloud-based solutions.

FREE-ENERGY CHANGES occur during a chemical reaction The least stable arrangement of the atoms during the reaction is called the transition state, and it occurs at an energy maximum How fast the reaction happens is determined by the free energy of activation, the free-energy difference between the substrate and the transition state The larger the free energy of activation, the slower the reaction

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the slower the reaction The difference in free energy between the transition state and the reactant(s) is called the free energy of activation

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The server and storage platforms that make up the Oracle Exadata Database Machine themselves will continue to evolve too For databases, having large volumes of frequently accessed data closest to the CPUs has always been a desirable method for speeding up performance Many predict that over coming generations, you will come to expect ever larger capacities of Flash and memory and will also see large footprints of physical disk storage disappear from the data center The impact of such changes in server and storage configurations should improve the performance of all workloads and also result in dramatic reductions in floor space, cooling, and electrical power required These advances could lead to solutions of new classes of business problems that can t be practically solved today

The reaction happens at a faster rate The catalyst is regenerated Enzymes do chemistry Their role is to make and break specific chemical bonds of the substrates at a faster rate and to do it without being consumed in the process At the end of each catalytic cycle, the enzyme is free to begin again with a new substrate molecule Since catalysis is simply making a reaction go faster, it follows that the activation energy of a catalyzed (faster) reaction is lower than the activation energy of an uncatalyzed reaction It s possible to say, then, that enzymes work by lowering the activation energy of the reaction they catalyze This is the same as saying that enzymes work because they work The question is how they lower the activation energy

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